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Thursday, July 28, 2016
Heart Association: Second Hand Marijuana Smoke Worse than Tobacco
By News Release @ 11:49 PM :: 4112 Views :: Health Care, Drugs

A minute of secondhand marijuana smoke may damage blood vessels

Study Highlights

  • Rats’ blood vessels took at least three times longer to recover function after only a minute of breathing secondhand marijuana smoke, compared to recovery after a minute of breathing secondhand tobacco smoke.
  • Arteries of rats and humans are similar in how they respond to secondhand tobacco smoke, so the response of rat arteries to secondhand marijuana smoke is likely to reflect how human arteries might respond.
  • With many states legalizing medical and recreational marijuana, and possible corporate expansion within the cannabis industry, this type of research is important to help understand the health consequences of exposure to secondhand marijuana smoke, researchers said. 

News Release from American Heart Association

DALLAS, July 27, 2016 — Rats’ blood vessels took at least three times longer to recover function after only a minute of breathing secondhand marijuana smoke, compared to recovery after a minute of breathing secondhand tobacco smoke, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

When rats inhaled secondhand marijuana smoke for one minute, their arteries carried blood less efficiently for at least 90 minutes, whereas similar exposure to secondhand tobacco smoke caused blood vessel impairment that recovered within 30 minutes.

“While the effect is temporary for both cigarette and marijuana smoke, these temporary problems can turn into long-term problems if exposures occur often enough and may increase the chances of developing hardened and clogged arteries,” said Matthew Springer, Ph.D., study senior author and professor of medicine at the University of California, San Francisco’s Division of Cardiology.

Blood vessel function was examined in rats before and after exposure to secondhand marijuana smoke at levels similar to real-world secondhand tobacco smoke.

“Arteries of rats and humans are similar in how they respond to secondhand tobacco smoke, so the response of rat arteries to secondhand marijuana smoke is likely to reflect how human arteries might respond,” Springer said.

Researchers also found the mere burning of the plant material appears responsible for the impaired blood vessels, not chemicals like nicotine and tetrahydrocannabinol (THC), the psychoactive ingredient in marijuana, nor rolling paper.

“There is widespread belief that, unlike tobacco smoke, marijuana smoke is benign,” Springer said.  “We in public health have been telling the public to avoid secondhand tobacco smoke for years, but we don't tell them to avoid secondhand marijuana smoke, because until now we haven’t had evidence that it can be harmful.”

Springer also noted that the increasing number of states legalizing medicinal and recreational marijuana, along with increasing potential for corporate expansion within the cannabis industry, makes it important to understand the health consequences of secondhand marijuana smoke exposure.

The inhalation of smoke should be avoided, regardless of whether it comes from tobacco, marijuana, or other sources. Inhaling smoke is bad for you – period, researchers said.

Co-authors are Xiaoyin Wang, M.D.; Ronak Derakhshandeh, M.S.; Jiangtao Liu, M.D.; Shilpa Narayan, B.S.; Pooneh Nabavizadeh, M.D.; Stephanie Le, B.A.; Olivia Danforth, B.S.; Kranthi Pinnamaneni, M.D.; Hilda Rodriguez, A.S.; Emmy Luu, B.S.; Richard Sievers, B.S.; Suzaynn Schick, Ph.D.; and Stanton Glantz, Ph.D. Author disclosures are on the manuscript.

The National Institutes of Health’s National Institute on Drug Abuse and a generous grant from Elfenworks Foundation funded the study.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at www.heart.org/corporatefunding.

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